Transcranial low-frequency pulsating electromagnetic fields (T-PEMF) as post-concussion syndrome treatment

Brain Injury/TBI, Pulsed Electro-Magnetic Field (PEMF) Therapy

A small but significant number of mild traumatic brain injuries (mTBI) result in development of persistent prolonged symptoms, including cognitive deficits, headaches, and mental fatigue. Such symptoms are called post-concussion syndrome (PCS), usually diagnosed according to the International Classification of Disease (ICD)-10 or the Diagnostic and Statistical Manual of Mental Disorder (DSM)-IV. However, the concept…

The National Brain Injury Rescue and Rehabilitation Study – a multicenter observational study of hyperbaric oxygen for mild traumatic brain injury with post-concussive symptoms

Brain Injury/TBI, Hyperbaric Oxygen Therapy (HBOT)

The National Brain Injury Rescue and Rehabilitation Project was established as a preliminary study to test the safety and practicality of multi-center hyperbaric oxygen administration for the post-concussive symptoms of chronic mild traumatic brain injury as a precursor to a pivotal, independent, multi-center, controlled clinical trial. This report presents the results for 32 subjects who…

Hyperbaric oxygen alleviates secondary brain injury after trauma through inhibition of TLR4/NF-κB signaling pathway

Brain Injury/TBI, Hyperbaric Oxygen Therapy (HBOT)

The aim of this study was to investigate the efficacy of hyperbaric oxygen in secondary brain injury after trauma and its mechanism in a rat model. A rat model of TBI was constructed using the modified Feeney’s free-fall method, and 60 SD rats were randomly divided into three groups – the sham group, the untreated…

Transcranial, Red/Near-Infrared Light-Emitting Diode Therapy to improve cognition in chronic traumatic brain injury

Brain Injury/TBI, Near Infrared (NIR)/Red Light Therapy

Study reviews the general topic of traumatic brain injury (TBI) and research utilizing transcranial photobiomodulation (tPBM) to improve cognition in chronic TBI using red/near-infrared (NIR) light-emitting diodes (LEDs) to deliver light to the head. Transcranial Photobiomodulation improves mitochondrial function increasing oxygen consumption, production of adenosine triphosphate (ATP), and improving cellular energy stores. Nitric oxide is…