The objective of this study was to examine long-term effects of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD). The research was implemented for a period of five years. For LLLT, a He-Ne Laser with continuous emission at 633 nm (0.1 mW/cm2) was used in patients with AMD of all stages (dry…
This was a randomized crossover double-blinded placebo-controlled trial to investigate if low-level laser therapy (LLLT) can affect biceps muscle performance, fatigue development, and biochemical markers of postexercise recovery. Cell and animal studies have suggested that LLLT can reduce oxidative stress and inflammatory responses in muscle tissue. But it remains uncertain whether these findings can translate…
Fibromyalgia is a chronic disorder characterized by widespread pain and tenderness. Low-level laser therapy (LLLT), an emerging nonpharmacological treatment, has been used for relieving musculoskeletal or neuropathic pain. The objective of this review and meta-analysis was to determine the efficacy of LLLT on patients with fibromyalgia. Asystematic review and meta-analysis of RCTs evaluating the effect…
Wound healing is a highly coordinated and complex process involving various cell types, chemical mediators and the surrounding extracellular matrix, resulting in a tightly orchestrated re-establishment of tissue integrity by specific cytokines. It consists of various dynamic processes including a series of overlapping phases: inflammation, proliferation, re-epithelialization and remodeling. One of the underlying mechanisms responsible…
Low-level laser therapy (LLLT) is a form of light therapy that triggers biochemical changes within cells. Photons are absorbed by cellular photoreceptors, triggering chemical alterations and potential biochemical benefits to the human body. LLLT has been used in pain management for years and is also known as cold laser therapy, which uses low-frequency continuous laser…
Low back pain is the leading cause of disability, with an estimated 632 million persons worldwide suffering and producing societal costs exceeding $100 billion annually in the United States. The use of low-level lasers (LLLT) has demonstrated beneficial effects for treating a range of painful musculoskeletal conditions, including low back pain. The Food and Drug…
The aim of the present study was to investigate the effect of low-level laser therapy (LLLT) on liver regeneration following hepatectomy. Background: LLLT has been found to modulate various biological processes. Twelve mature male rats were used. The liver was exposed, and 70% of it was excised. The rats were assigned randomly to two groups:…
Low-power laser irradiation of red light has been recognized as a promising tool across a vast variety of biomedical applications. However, deep understanding of the molecular mechanisms behind laser-induced cellular effects remains a significant challenge. Here, we investigated mechanisms involved in the death process in human hepatic cell line Huh7 at a laser irradiation. We…
This study investigated the effects of low-level laser therapy (LLLT) in the liver function, structure and inflammation in a experimental model of carbon tetrachloride (CCl(4))-induced liver cirrhosis. Wistar rats were divided into Control, LLLT, CCl(4) and CCl(4) +LLLT groups. CCl(4) groups received CCl(4) (0.4 g kg(-1); i.p.), three times a week, for 12 weeks. A…
Low-Level Laser Therapy (LLLT), also referred to as photobiology or bio-stimulation, involves the application of low-power monochromatic and coherent light to injuries and lesions. LLLT is a treatment that utilises light of a single wavelength; it emits no heat, sound, or vibration. Instead of producing a thermal effect, LLLT acts via non-thermal or photochemical reactions…