Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation

Anti-Aging, Cognitive Enhancement, Hyperbaric Oxygen Therapy (HBOT)

There is a real need for new interventions for Alzheimer’s disease (AD). Hyperbaric oxygen therapy (HBOT), the medical administration of 100% oxygen at conditions greater than 1 atmosphere absolute, has been used successfully to treat several neurological conditions, but its effects on AD pathology have never been thoroughly examined. Therefore, we exposed old triple-transgenic (3xTg) and…

Evaluation of Radiofrequency Devices in Aesthetic Medicine: A Preliminary Report

Anti-Aging, Pulsed Electro-Magnetic Field (PEMF) Therapy

In recent years, there has been an explosion of non-invasive devices to promote wrinkle, cellulite and fat reduction in patients who do not want invasive surgery. According to the American Society of Plastic Surgery in 2015 the annual number of minimal or non-invasive procedures has nearly tripled since 2000. In 2013, the International Society of…

Mild Hyperbaric Oxygen Inhibits Growth-related Decrease in Muscle Oxidative Capacity of Rats with Metabolic Syndrome

Anti-Aging, Hyperbaric Oxygen Therapy (HBOT)

Metabolic syndrome is linked to physical inactivity and consumption of a high-fat and high-calorie diet and is characterized by obesity, high blood pressure, increased blood glucose levels, and hyperlipidemia1). Skeletal muscle is the primary site of insulin action and glucose metabolism. Reduced oxidative capacity in skeletal muscle impairs glucose metabolism and increases the risk of…

Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial

Anti-Aging, Cognitive Enhancement, Hyperbaric Oxygen Therapy (HBOT)

More than half of community-dwelling individuals sixty years and older express concern about declining cognitive abilities. The current study’s aim was to evaluate hyperbaric oxygen therapy (HBOT) effect on cognitive functions in healthy aging adults. A randomized controlled clinical trial randomized 63 healthy adults (>64) either to HBOT(n=33) or control arms(n=30) for three months. Primary…

Safety and Efficacy of 630-nm Red Light on Cognitive Function in Older Adults With Mild to Moderate Alzheimer’s Disease: Protocol for a Randomized Controlled Study

Anti-Aging, Near Infrared (NIR)/Red Light Therapy

Studies have shown that excess formaldehyde accumulation in the brain accelerates cognitive decline in people with Alzheimer’s disease (AD). Recently, reports from our research team revealed that red light treatment (RLT) improved memory in AD mice by activating formaldehyde dehydrogenase (FDH) and thus reducing formaldehyde levels. Here, we developed a medical RLT device to investigate…

Does photobiomodulation influence ageing? 

Anti-Aging, Near Infrared (NIR)/Red Light Therapy

Mitochondria play key roles in regulating the ageing process. When their membrane potential and function declines, their production of adenosine triphosphate (ATP) reduces and they can signal cell death. This is particularly marked in the energy demanding central nervous system, where the neurons and glia, undergo some key structural and functional changes during ageing. Over…