Low-Level Laser Therapy (LLLT), also referred to as photobiology or bio-stimulation, involves the application of low-power monochromatic and coherent light to injuries and lesions. LLLT is a treatment that utilises light of a single wavelength; it emits no heat, sound, or vibration. Instead of producing a thermal effect, LLLT acts via non-thermal or photochemical reactions…
Low-Level Laser Therapy (LLLT), also referred to as photobiology or bio-stimulation, involves the application of low-power monochromatic and coherent light to injuries and lesions. LLLT is a treatment that utilises light of a single wavelength; it emits no heat, sound, or vibration. Instead of producing a thermal effect, LLLT acts via non-thermal or photochemical reactions…
The management of musculoskeletal disorders is an increasing challenge to clinicians. Successful treatment relies on a wide range of multidisciplinary interventions. Adjunctive hyperbaric oxygen (HBO) therapy has been used as an orthopaedic treatment for several decades. Positive outcomes have been reported by many authors for orthopaedic infections, wound healing, delayed union and non-union of fractures,…
Increasing evidence suggests that an exogenous electromagnetic field might be involved in many biologic processes which are of great importance for therapeutic interventions. Pulsed electromagnetic fields (PEMFs) are known to be a noninvasive, safe and effective therapy agent without apparent side effects. Numerous studies have shown that PEMFs possess the potential to become a stand-alone…
ABSTRACT Bone and soft‑tissue sarcoma constitute more than 20% of pediatric solid malignant cancers and almost 1% of adult solid malignant cancer. Musculoskeletal (MSK) disorders are the heterogeneous group of mesenchymal malignancies. Early diagnosis of these has a substantial effect on optimal treatment and quality of life of these patients. New applications and techniques have…
Mandibular condylar chondrocyte apoptosis is mainly responsible for the development and progression of temporomandibular joint osteoarthritis (TMJ-OA). Interleukin-1β (IL-1β) generally serves an agent that induces chondrocyte apoptosis. Hyperbaric oxygen (HBO) treatment increases proteoglycan synthesis in vivo.We explore the protective effect of HBO on IL-1β-induced mandibular condylar chondrocyte apoptosis in rats and the potential molecular mechanisms.…
Bone defects remain a challenge for patients and orthopaedic surgeons. Autologous transfer of cancellous bone grafts remains the standard of care. However, in recent years various osteoinductive substitute materials, such as platelet rich plasma (PRP) and hyperbaric oxygen therapy (HBO) have been shown to improve bone healing. This study evaluates the effects of a combined…
This study presented an insight into the effect of hyperbaric oxygen (HBO) on spinal cord injury (SCI), aiming to uncover the dynamics of high-mobility group protein B1 (HMGB1) and nuclear factor κB (NF-κB) after HBO intervention in rats with acute SCI. Objective. Prognosis of SCI is directly linked with the control of secondary injury, in…
This study presented an insight into the effect of hyperbaric oxygen (HBO) on spinal cord injury (SCI), aiming to uncover the dynamics of high-mobility group protein B1 (HMGB1) and nuclear factor κB (NF-κB) after HBO intervention in rats with acute SCI. Objective. Prognosis of SCI is directly linked with the control of secondary injury, in…
The cellular and molecular mechanism through which hyperbaric oxygen therapy (HBO) improves osteonecrosis (ON) is unclear. The present study therefore examined the effect of HBO, pressure and hyperoxia on RANKL‐induced osteoclast formation in RAW 264.7 cells and human peripheral blood monocytes (PBMC). Daily exposure to HBO (2.4 ATA, 97% O2, 90 min), hyperbaric pressure (2.4 ATA,…