The effect of low-level laser therapy and physical exercise on pain, stiffness, function, and spatiotemporal gait variables in subjects with bilateral knee osteoarthritis: a blind randomized clinical trial

This study sought to evaluate the effects of individual and combination therapies (low-level laser therapy and physical exercises) on pain, stiffness, function, and spatiotemporal gait variables in subjects with bilateral knee osteoarthritis. It concluded that a combination of exercise and laser therapy provided the best results for the other gait variables (cadence and duration of…

Low frequency pulsed electromagnetic field — A viable alternative therapy for arthritis

Arthritis refers to more than 100 disorders of the musculoskeletal system. The existing pharmacological interventions for arthritis offer only symptomatic relief and they are not definitive and curative. Magnetic healing has been known from antiquity and it is evolved to the present times with the advent of electromagnetism. The original basis for the trial of…

Effects of Pulsed Electromagnetic Field Therapy on Pain, Stiffness and Physical Function in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Knee osteoarthritis is currently one of the most common joint diseases worldwide. Pulsed electromagnetic field therapy has become popular among patients with knee osteoarthritis in recent years. However, the efficacy of this therapy on joint pain, joint stiffness and physical function is regarded as controversial in published clinical trials and systematic reviews. Several new randomized…

Incorporation of photobiomodulation therapy into a therapeutic exercise program for knee osteoarthritis

This was a placebo-controlled, randomized, clinical trial to investigate the clinical effects of incorporation of phototherapy in a therapeutic exercise program for individuals with knee osteoarthritis (OA) when compared to a group that received exercise alone and to a group that received exercise + placebo phototherapy. Exercise + active phototherapy was significantly more effective than…

Review of Literature on Low-level Laser Therapy Benefits for Nonpharmacological Pain Control in Chronic Pain and Osteoarthritis

Low-level laser therapy (LLLT) is a form of light therapy that triggers biochemical changes within cells. Photons are absorbed by cellular photoreceptors, triggering chemical alterations and potential biochemical benefits to the human body. LLLT has been used in pain management for years and is also known as cold laser therapy, which uses low-frequency continuous laser…

Hyperbaric oxygen protects mandibular condylar chondrocytes from interleukin-1β-induced apoptosis via the P13K/AKT signaling pathway

Mandibular condylar chondrocyte apoptosis is mainly responsible for the development and progression of temporomandibular joint osteoarthritis (TMJ-OA). Interleukin-1β (IL-1β) generally serves an agent that induces chondrocyte apoptosis. Hyperbaric oxygen (HBO) treatment increases proteoglycan synthesis in vivo.We explore the protective effect of HBO on IL-1β-induced mandibular condylar chondrocyte apoptosis in rats and the potential molecular mechanisms.…