Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

Hypoxia is associated with increased resistance to chemo- and radiation-therapy. Hyperoxic treatment (hyperbaric oxygen) has previously been shown to potentiate the effect of some forms of chemotherapy, and this has been ascribed to enhanced cytotoxicity or neovascularisation. The aim of this study was to elucidate whether hyperoxia also enhances any actual uptake of 5FU (5-fluorouracil)…

A 60-Hz sinusoidal magnetic field induces apoptosis of prostate cancer cells through reactive oxygen species

This study explores the effects of power frequency magnetic fields (MF) on cell growth in prostate cancer, DU145, PC3, and LNCaP cells were examined in vitro. The cells were exposed to various intensities and durations of 60-Hz sinusoidal MF in combination with various serum concentrations in the media. To analyze MF effects on cell growth,…

Effect of Electromagnetic Field and Allicin as Natural Extract on Hepatocellular Carcinoma (HepG2)

Cancer is one of the major public burdens worldwide. It is a multicellular disease that can arise from all cell type. In the recent decades, the number of cancer related showed a clear elevation, in turn creating huge health and economic problems. Non-ionizing Electromagnetic Fields (EMF), from extremely-low frequency to radiofrequency, have been shown to…

Emerging Ionizing and Non-Ionizing Radiation for Treatment of Musculoskeletal Disorders and Malignancies

ABSTRACT Bone and soft‑tissue sarcoma constitute more than 20% of pediatric solid malignant cancers and almost 1% of adult solid malignant cancer. Musculoskeletal (MSK) disorders are the heterogeneous group of mesenchymal malignancies. Early diagnosis of these has a substantial effect on optimal treatment and quality of life of these patients. New applications and techniques have…